AMD logo AMD MI250 vs Nvidia logo Nvidia RTX 4090

The MI250 has 5.3x the memory and 3.2x the bandwidth. 1 provider lists it, against 19 for the RTX 4090.

At a glance

Memory

5.3x more on MI250

MI250
128 GB
RTX 4090
24 GB

Memory bandwidth

3.2x higher on MI250

MI250
3.20 TB/s
RTX 4090
1.01 TB/s

Cheapest on-demand

MI250 is not sold on demand

MI250
--
RTX 4090
$0.32 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI250 RTX 4090 Difference
On-demand No on-demand listings $0.44 /GPU/hr from $0.32
Reserved -- /GPU/hr from $1.30 (12 mo) $0.52 /GPU/hr from $0.28 (3 mo)
Spot No spot listings $0.34 /GPU/hr from $0.16

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved on the MI250: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI250 vs RTX 4090 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 RTX 4090 Difference
Memory
Capacity 128 GB HBM2e 24 GB GDDR6X 5.3x more on MI250
Bandwidth 3,200 GB/s 1,010 GB/s 3.2x higher on MI250
Bus width 8,192-bit 384-bit 21x wider on MI250
Compute · dense
FP8 Not supported 330.3 TFLOPS RTX 4090 only
FP16 / BF16 362.1 TFLOPS 165.2 TFLOPS 2.2x higher on MI250
INT8 362.1 TOPS 660.6 TOPS 82% higher on RTX 4090
FP32 90.5 TFLOPS 82.6 TFLOPS 10% higher on MI250
FP64 45.3 TFLOPS Not supported MI250 only
Platform
Interconnect Infinity Fabric 400 GB/s PCIe only Infinity Fabric on MI250 only
Board power 500 W 450 W 11% higher on MI250
Released Q4 2021 Q4 2022 11 months newer on RTX 4090
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP8FP16BF16TF32FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and RTX 4090 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

1 provider list the MI250 and 19 the RTX 4090. Every listing is on the MI250 page and the RTX 4090 page.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI250 was last updated on Sept. 14, 2026, and for Nvidia RTX 4090 on Sept. 14, 2026.