MI250 vs MI300X
The MI250 offers 128GB with CDNA2, while the MI300X provides 192GB with CDNA3. Choose MI250 for lower cost, MI300X for higher performance.
Overview
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AMD MI250
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AMD MI300X
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| Summary | Previous-gen AMD data center GPU for HPC and scientific computing. | AMD's flagship data center GPU for large-model inference. |
| Architecture | CDNA2 | CDNA 3 |
| Memory | 128GB HBM2e | 192GB HBM3 |
| Memory Bandwidth | 3,200 GB/s | 5,300 GB/s |
| Performance | 362 TFLOPS (FP16) | 1,307 TFLOPS (FP16) |
| Release Date | Q4 2021 | Q4 2023 |
| Performance Segment | High Performance | High Performance |
| Datasheet | Link | Link |
Price comparison
MI250 Pricing
Pricing for the MI250 is consistent across 2 cloud providers, averaging around $1.48/hr per GPU. The range is tight, but the lowest current rate is $1.30/hr.
How we sort results
Default ranking
Our algorithm weighs five factors to find the most relevant matches for you:
- Price: We blend total hourly price with price-per-GPU to balance affordability and value.
- Specs: We favor offers with higher CPU, RAM, and GPU Memory.
- Billing: We favor on-demand billing for simplicity and flexibility over spot instances, reservations, and custom quotes.
- Location: We blend both datacenter proximity and provider HQ location. Datacenter location matters for latency, while HQ location matters for compliance and support.
- Provider diversity: Each time a provider appears in the list, their subsequent offerings are ranked a little lower, so one provider's offerings don't crowd out the top positions.
Sorting and filtering
Click "View all offerings" to access the full list with sortable columns and filters for billing type, GPU count, vCPUs, and RAM.
Transparency and funding
Ads and sponsors: Any paid placements are fixed at the top and clearly labeled as sponsored content.
Affiliates: Any affiliate links will be indicated to you as well. We may earn a commission if you click them, but this never influences the ranking order.
| Provider | GPUs | Billing | Total/h | |
|---|---|---|---|---|
Cirrascale
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4x | Reserved (12mo) 12-month contract: $3,743/month | $5.20 | View |
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Cirrascale
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4x | Reserved (6mo) 6-month contract: $4,211/month | $5.85 | View |
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Cirrascale
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4x | Reserved (3mo) 3-month contract: $4,445/month | $6.17 | View |
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Cirrascale
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4x | Reserved (1mo) 1-month contract: $4,679/month | $6.50 | View |
CUDO
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1x | Custom Custom terms negotiated with the provider. | Custom | View |
| No offerings matching your filters. | ||||
MI300X Pricing
Listings for the MI300X reach $7.86/hr, often reflecting a premium for high availability. However, you might be able to find available instances from as low as $0.95/hr per GPU (spot instance).
How we sort results
Default ranking
Our algorithm weighs five factors to find the most relevant matches for you:
- Price: We blend total hourly price with price-per-GPU to balance affordability and value.
- Specs: We favor offers with higher CPU, RAM, and GPU Memory.
- Billing: We favor on-demand billing for simplicity and flexibility over spot instances, reservations, and custom quotes.
- Location: We blend both datacenter proximity and provider HQ location. Datacenter location matters for latency, while HQ location matters for compliance and support.
- Provider diversity: Each time a provider appears in the list, their subsequent offerings are ranked a little lower, so one provider's offerings don't crowd out the top positions.
Sorting and filtering
Click "View all offerings" to access the full list with sortable columns and filters for billing type, GPU count, vCPUs, and RAM.
Transparency and funding
Ads and sponsors: Any paid placements are fixed at the top and clearly labeled as sponsored content.
Affiliates: Any affiliate links will be indicated to you as well. We may earn a commission if you click them, but this never influences the ranking order.
| Provider | GPUs | Billing | Total/h | |
|---|---|---|---|---|
Runpod
Our sponsor
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1x | On-Demand Pay-as-you-go pricing. No term commitments. | $1.99 | View |
DigitalOcean
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1x | On-Demand Pay-as-you-go pricing. No term commitments. | $1.99 | View |
Hot Aisle
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1x | On-Demand Pay-as-you-go pricing. No term commitments. | $1.99 | View |
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Hot Aisle
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1x | On-Demand Pay-as-you-go pricing. No term commitments. | $1.99 | View |
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DigitalOcean
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8x | On-Demand Pay-as-you-go pricing. No term commitments. | $15.92 | View |
Crusoe
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8x | On-Demand Pay-as-you-go pricing. No term commitments. | $27.60 | View |
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Hot Aisle
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2x | On-Demand Pay-as-you-go pricing. No term commitments. | $3.98 | View |
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Hot Aisle
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4x | On-Demand Pay-as-you-go pricing. No term commitments. | $7.96 | View |
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Runpod
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1x | Reserved (12mo) Reserved capacity with a 1-year minimum commitment. | $1.51 | View |
Vultr
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8x | Reserved (24mo) Reserved capacity with a 24-month minimum commitment. | $14.80 | View |
Azure
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8x | Spot Variable spot pricing with potential interruptions. | $11.62 | View |
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Crusoe
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8x | Spot Variable spot pricing with potential interruptions. | $7.60 | View |
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Runpod
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1x | Reserved (6mo) Reserved capacity with a 6-month minimum commitment. | $1.59 | View |
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Cirrascale
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8x | Reserved (12mo) 12-month contract: $17,999/month | $24.99 | View |
Oracle Cloud
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8x | On-Demand Pay-as-you-go pricing. No term commitments. | $48.00 | View |
| No offerings matching your filters. | ||||
Heads up: We do our best to keep these prices accurate. However, cloud costs may fluctuate based on region, usage, and other factors not listed here. These are estimates based on common setups and are for informational purposes only. Always verify current rates with the provider before provisioning.
Alternative GPUs
Here's how these GPUs compare against alternatives:
AMD MI250
vs
Nvidia A100
AMD MI250
vs
Nvidia V100
AMD MI300X
vs
Nvidia H100
AMD MI300X
vs
AMD MI325X
Our data for AMD MI250 was last updated on March 25, 2026, and for AMD MI300X on March 25, 2026.