AMD logo AMD MI250 vs Nvidia logo Nvidia RTX PRO 5000

The MI250 has 2.7x the memory and 2.4x the bandwidth.

At a glance

Memory

2.7x more on MI250

MI250
128 GB
RTX PRO 5000
48 GB

Memory bandwidth

2.4x higher on MI250

MI250
3.20 TB/s
RTX PRO 5000
1.34 TB/s

Cheapest on-demand

MI250 is not sold on demand

MI250
--
RTX PRO 5000
$0.58 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI250 RTX PRO 5000 Difference
On-demand No on-demand listings -- /GPU/hr from $0.58
Reserved -- /GPU/hr from $1.30 (12 mo) $0.92 /GPU/hr from $0.50 (24 mo)
Spot No spot listings -- /GPU/hr from $0.14

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved on the MI250 and on-demand and spot on the RTX PRO 5000: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI250 vs RTX PRO 5000 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 RTX PRO 5000 Difference
Memory
Capacity 128 GB HBM2e 48 GB GDDR7 2.7x more on MI250
Bandwidth 3,200 GB/s 1,344 GB/s 2.4x higher on MI250
Bus width 8,192-bit 512-bit 16x wider on MI250
Compute · dense
FP4 Not supported 1,032 TFLOPS RTX PRO 5000 only
FP8 Not supported 516 TFLOPS RTX PRO 5000 only
FP16 / BF16 362.1 TFLOPS 258 TFLOPS 40% higher on MI250
INT8 362.1 TOPS 516 TOPS 43% higher on RTX PRO 5000
FP32 90.5 TFLOPS 65 TFLOPS 39% higher on MI250
FP64 45.3 TFLOPS Not supported MI250 only
Platform
Interconnect Infinity Fabric 400 GB/s PCIe only Infinity Fabric on MI250 only
Board power 500 W 300 W 67% higher on MI250
Released Q4 2021 Q1 2025 3 years newer on RTX PRO 5000
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP4FP8FP16BF16TF32FP32INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and RTX PRO 5000 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI250 was last updated on Sept. 14, 2026, and for Nvidia RTX PRO 5000 on Sept. 14, 2026.