AMD logo AMD MI250 vs Nvidia logo Nvidia Quadro RTX 6000

The MI250 is newer, with 5.3x the memory and 4.8x the bandwidth.

At a glance

Memory

5.3x more on MI250

MI250
128 GB
Quadro RTX 6000
24 GB

Memory bandwidth

4.8x higher on MI250

MI250
3,200 GB/s
Quadro RTX 6000
672 GB/s

Cheapest on-demand

MI250 is not sold on demand

MI250
--
Quadro RTX 6000
$0.13 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI250 Quadro RTX 6000 Difference
On-demand No on-demand listings -- /GPU/hr from $0.13
Reserved -- /GPU/hr from $1.30 (12 mo) -- /GPU/hr from $0.12 (12 mo)

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved on the MI250 and on-demand and reserved on the Quadro RTX 6000: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI250 vs Quadro RTX 6000 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 Quadro RTX 6000 Difference
Memory
Capacity 128 GB HBM2e 24 GB GDDR6 5.3x more on MI250
Bandwidth 3,200 GB/s 672 GB/s 4.8x higher on MI250
Bus width 8,192-bit 384-bit 21x wider on MI250
Compute · dense
FP16 / BF16 362.1 TFLOPS 130.5 TFLOPS 2.8x higher on MI250
INT8 362.1 TOPS 261 TOPS 39% higher on MI250
FP32 90.5 TFLOPS 16.3 TFLOPS 5.6x higher on MI250
FP64 45.3 TFLOPS Not supported MI250 only
Platform
Interconnect Infinity Fabric 400 GB/s NVLink 100 GB/s 4x higher on MI250
Board power 500 W 295 W 69% higher on MI250
Released Q4 2021 Q3 2018 3 years newer on MI250
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP16FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and Quadro RTX 6000 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI250 was last updated on Sept. 14, 2026, and for Nvidia Quadro RTX 6000 on Sept. 14, 2026.