AMD MI250
vs
Nvidia Quadro RTX 6000
The MI250 is newer, with 5.3x the memory and 4.8x the bandwidth.
At a glance
Memory
5.3x more on MI250
- MI250
- 128 GB
- Quadro RTX 6000
- 24 GB
Memory bandwidth
4.8x higher on MI250
- MI250
- 3,200 GB/s
- Quadro RTX 6000
- 672 GB/s
Cheapest on-demand
MI250 is not sold on demand
- MI250
- --
- Quadro RTX 6000
- $0.13 /GPU/hr
Price comparison
Median price per GPU per hour by billing type, with the cheapest listing under it.
| Billing | MI250 | Quadro RTX 6000 | Difference |
|---|---|---|---|
| On-demand | No on-demand listings | -- /GPU/hr from $0.13 | |
| Reserved | -- /GPU/hr from $1.30 (12 mo) | -- /GPU/hr from $0.12 (12 mo) |
Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved on the MI250 and on-demand and reserved on the Quadro RTX 6000: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.
Price history
MI250 vs Quadro RTX 6000 price history
Weekly median on-demand price per GPU per hour
Specs comparison
| Spec | MI250 | Quadro RTX 6000 | Difference |
|---|---|---|---|
| Memory | |||
| Capacity | 128 GB HBM2e | 24 GB GDDR6 | 5.3x more on MI250 |
| Bandwidth | 3,200 GB/s | 672 GB/s | 4.8x higher on MI250 |
| Bus width | 8,192-bit | 384-bit | 21x wider on MI250 |
| Compute · dense | |||
| FP16 / BF16 | 362.1 TFLOPS | 130.5 TFLOPS | 2.8x higher on MI250 |
| INT8 | 362.1 TOPS | 261 TOPS | 39% higher on MI250 |
| FP32 | 90.5 TFLOPS | 16.3 TFLOPS | 5.6x higher on MI250 |
| FP64 | 45.3 TFLOPS | Not supported | MI250 only |
| Platform | |||
| Interconnect | Infinity Fabric 400 GB/s | NVLink 100 GB/s | 4x higher on MI250 |
| Board power | 500 W | 295 W | 69% higher on MI250 |
| Released | Q4 2021 | Q3 2018 | 3 years newer on MI250 |
| Precision | |||
| Supported formats | FP16BF16FP32FP64INT4INT8 | FP16FP32INT4INT8 | |
Compute: Vendor peak figures, dense and per GPU. Not measured throughput.
Source: MI250 datasheet and Quadro RTX 6000 datasheet.
Where to rent them
Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.
| Provider | MI250 | Quadro RTX 6000 |
|---|---|---|
|
|
$1.30 /GPU/hr Reserved | -- |
|
|
-- | $0.13 /GPU/hr On-demand |
|
|
-- | $1.50 /GPU/hr On-demand |
|
|
-- | $0.69 /GPU/hr On-demand |
Similar GPUs
Other comparisons in the same class.
-
Nvidia A100
80 GB HBM2e · 40% less bandwidth than the MI250
From $0.40 /GPU/hr Compare -
AMD MI300X
192 GB HBM3 · 66% more bandwidth than the MI250
From $2.59 /GPU/hr Compare -
Nvidia V100
32 GB HBM2 · 72% less bandwidth than the MI250
From $0.08 /GPU/hr Compare -
Nvidia RTX A6000
48 GB GDDR6 · released Q4 2020
From $0.40 /GPU/hr Compare
Our data for AMD MI250 was last updated on Sept. 14, 2026, and for Nvidia Quadro RTX 6000 on Sept. 14, 2026.