AMD MI250
vs
Nvidia RTX 5880 Ada
A data center GPU against a workstation card, one CDNA2 and one Ada Lovelace: 128 GB HBM2e against 48 GB GDDR6, 3.3x the memory bandwidth on the MI250, and Infinity Fabric 400 GB/s on the MI250 where the RTX 5880 Ada is PCIe only.
At a glance
Updated 9 hours ago- Memory
- 128 GB
- HBM2e
- Memory bandwidth
- 3.20 TB/s
- From
- --
- Not sold on demand · 1 provider
- Memory
- 48 GB
- GDDR6
- Memory bandwidth
- 960 GB/s
- From
- --
Price comparison
Cheapest listed price per GPU per hour by billing type, and the median across providers.
| Billing | MI250 | RTX 5880 Ada | Difference |
|---|---|---|---|
| On-demand | Not sold on demand | -- | |
| Reserved | $1.30 | No reserved listings | |
| Median | $1.50 | -- |
Median: Median across providers, one vote each, so a large catalog does not outweigh a small one.
Price history
MI250 vs RTX 5880 Ada price history
Weekly median on-demand price per GPU per hour
Specs comparison
| Spec | MI250 | RTX 5880 Ada | Difference |
|---|---|---|---|
| Memory | |||
| Capacity | 128 GB HBM2e | 48 GB GDDR6 | 2.7x more on MI250 |
| Bandwidth | 3,200 GB/s | 960 GB/s | 3.3x higher on MI250 |
| Bus width | 8,192-bit | 384-bit | 21x wider on MI250 |
| Compute · dense | |||
| FP8 | Not supported | 554.2 TFLOPS | RTX 5880 Ada only |
| FP16 / BF16 | 362.1 TFLOPS | 277.1 TFLOPS | 1.3x higher on MI250 |
| INT8 | 362.1 TOPS | ||
| FP32 | 90.5 TFLOPS | 69.3 TFLOPS | 1.3x higher on MI250 |
| FP64 | 45.3 TFLOPS | Not supported | MI250 only |
| Platform | |||
| Interconnect | Infinity Fabric 400 GB/s | PCIe only | Infinity Fabric on MI250 only |
| Board power | 500 W | 285 W | 1.8x higher on MI250 |
| Released | Q4 2021 | Q1 2024 | 2 years newer on RTX 5880 Ada |
| Precision | |||
| Supported formats | FP16BF16FP32FP64INT4INT8 | FP8FP16BF16TF32FP32INT4INT8 | |
Compute: Vendor peak figures, dense and per GPU. Not measured throughput.
Source: MI250 datasheet and RTX 5880 Ada datasheet.
Where to rent them
Providers listing these GPUs, those with both first, so you can switch without moving clouds.
| Provider | MI250 /GPU/hr | RTX 5880 Ada /GPU/hr |
|---|---|---|
Cirrascale
|
Reserved (12mo) $1.30 | -- |
Similar GPUs
Other comparisons in the same class.
Our data for AMD MI250 was last updated on Sept. 7, 2026, and for Nvidia RTX 5880 Ada on Sept. 7, 2026.