Overview
AMD MI250
Previous-gen AMD data center GPU for HPC and scientific computing.
Nvidia RTX 4500 Ada
Compact Ada Lovelace professional GPU for AI and 3D workflows.
Memory per GPU
5.3x more on MI250
MI250
RTX 4500 Ada
Memory bandwidth
7.4x higher on MI250
MI250
RTX 4500 Ada
GPU interconnect
MI250
RTX 4500 Ada
Precision support
MI250
RTX 4500 Ada
Highlighted formats are supported by only one of the two.
Architecture
MI250
RTX 4500 Ada
Released
2 years newer on RTX 4500 Ada
MI250
RTX 4500 Ada
Source: MI250 datasheet and RTX 4500 Ada datasheet.
Price comparison
Cheapest on-demand
MI250
RTX 4500 Ada
Typical rate
MI250
RTX 4500 Ada
Median across providers, one vote each, so a large catalog does not outweigh a small one.
Full price range
MI250
RTX 4500 Ada
Lowest to highest listing per GPU-hour, across on-demand, spot, reserved and custom.
Providers listing it
MI250
RTX 4500 Ada
Heads up: We do our best to keep these specs & prices accurate. However, cloud costs may fluctuate based on region, usage, and other factors not listed here. These are estimates based on common setups and are for informational purposes only. Always verify current rates & exact specs with the provider before provisioning.
Offers and availability
How this list works
Order
Each provider appears once per GPU. We pick the one configuration that speaks for that provider, and rank on it in this order:
- Availability: in stock, then waitlist, then not reported, then out of stock. A price you can act on outranks a cheaper one you cannot.
- Billing type: on-demand first, then reserved, then spot, then quote-only. On-demand leads because it is the only rate you can hold without committing to anything.
- Price: the lowest per-GPU hourly rate the provider lists, converted to USD.
The configuration we pick is chosen the same way, availability before billing before price. The rest of that provider's configurations are on the GPU's own page.
Ties sort alphabetically. Reserved rates are not separated by term length, so a three-year commitment can sit above a one-month one: the label beneath each price says which you are looking at. Providers who publish no rate are listed last within their group.
Transparency and funding
- Ads and sponsors: Paid placements sit at the top of the list and are always labeled as sponsored content. Sponsorship never influences the organic ranking itself.
- Affiliates: Affiliate links are marked. We may earn a commission if you click them, but commissions never affect the order.
- Prices: Shown in USD, converted at daily reference rates where a provider publishes in another currency. A month means 720 hours. How we estimate costs.
MI250 Offers
No provider publishes a stock status, 1 more publish no status.
RTX 4500 Ada Offers
No provider publishes a stock status.
No active offerings found
Similar GPUs
Other comparisons in the same class:
Our data for AMD MI250 was last updated on Aug. 21, 2026, and for Nvidia RTX 4500 Ada on Aug. 21, 2026.