AMD MI250
vs
Nvidia RTX 4080
A data center GPU against a consumer card, one CDNA2 and one Ada Lovelace: 128 GB HBM2e against 16 GB GDDR6X, 4.5x the memory bandwidth on the MI250, and Infinity Fabric 400 GB/s on the MI250 where the RTX 4080 is PCIe only.
At a glance
Updated 23 minutes ago- Memory
- 128 GB
- HBM2e
- Memory bandwidth
- 3.20 TB/s
- From
- --
- Not sold on demand · 1 provider
- Memory
- 16 GB
- GDDR6X
- Memory bandwidth
- 717 GB/s
- From
- $0.25 /GPU/hr
- 5 providers
Price comparison
Cheapest listed price per GPU per hour by billing type, and the median across providers.
| Billing | MI250 | RTX 4080 | Difference |
|---|---|---|---|
| On-demand | Not sold on demand | $0.25 | |
| Spot | No spot listings | $0.11 | |
| Reserved | $1.30 | No reserved listings | |
| Median | $1.50 | $0.27 | 5.7x more expensive on MI250 |
Median: Median across providers, one vote each, so a large catalog does not outweigh a small one.
Price history
MI250 vs RTX 4080 price history
Weekly median on-demand price per GPU per hour
Specs comparison
| Spec | MI250 | RTX 4080 | Difference |
|---|---|---|---|
| Memory | |||
| Capacity | 128 GB HBM2e | 16 GB GDDR6X | 8x more on MI250 |
| Bandwidth | 3,200 GB/s | 717 GB/s | 4.5x higher on MI250 |
| Bus width | 8,192-bit | 256-bit | 32x wider on MI250 |
| Compute · dense | |||
| FP8 | Not supported | 194.9 TFLOPS | RTX 4080 only |
| FP16 / BF16 | 362.1 TFLOPS | 97.5 TFLOPS | 3.7x higher on MI250 |
| INT8 | 362.1 TOPS | 389.9 TOPS | 1.1x higher on RTX 4080 |
| FP32 | 90.5 TFLOPS | 48.7 TFLOPS | 1.9x higher on MI250 |
| FP64 | 45.3 TFLOPS | Not supported | MI250 only |
| Platform | |||
| Interconnect | Infinity Fabric 400 GB/s | PCIe only | Infinity Fabric on MI250 only |
| Board power | 500 W | 320 W | 1.6x higher on MI250 |
| Released | Q4 2021 | Q4 2022 | 12 months newer on RTX 4080 |
| Precision | |||
| Supported formats | FP16BF16FP32FP64INT4INT8 | FP8FP16BF16TF32FP32INT4INT8 | |
Compute: Vendor peak figures, dense and per GPU. Not measured throughput.
Source: MI250 datasheet and RTX 4080 datasheet.
Where to rent them
Providers listing these GPUs, those with both first, so you can switch without moving clouds.
| Provider | MI250 /GPU/hr | RTX 4080 /GPU/hr |
|---|---|---|
Cirrascale
|
Reserved (12mo) $1.30 | -- |
GPUhub
|
-- | On-Demand $0.25 |
Theta EdgeCloud
|
-- | On-Demand $0.26 |
Salad
|
-- | On-Demand $0.28 |
SwissGPU
|
-- | On-Demand $0.25 |
Runpod
|
-- | On-Demand $0.27 |
Similar GPUs
Other comparisons in the same class.
Our data for AMD MI250 was last updated on Sept. 7, 2026, and for Nvidia RTX 4080 on Sept. 7, 2026.