AMD logo AMD MI250 vs Nvidia logo Nvidia RTX 4060

A data center GPU against a consumer card, one CDNA2 and one Ada Lovelace: 128 GB HBM2e against 8 GB GDDR6, 12x the memory bandwidth on the MI250, and Infinity Fabric 400 GB/s on the MI250 where the RTX 4060 is PCIe only.

At a glance

Updated 23 minutes ago
Memory
128 GB
HBM2e
Memory bandwidth
3.20 TB/s
From
--
Not sold on demand · 1 provider
Memory
8 GB
GDDR6
Memory bandwidth
272 GB/s
From
$0.08 /GPU/hr
3 providers

Price comparison

Cheapest listed price per GPU per hour by billing type, and the median across providers.

Billing MI250 RTX 4060 Difference
On-demand Not sold on demand $0.08
Spot No spot listings $0.05
Reserved $1.30 $0.21 6.3x more expensive on MI250
Median $1.50 $0.10 15x more expensive on MI250

Median: Median across providers, one vote each, so a large catalog does not outweigh a small one.

Price history

MI250 vs RTX 4060 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 RTX 4060 Difference
Memory
Capacity 128 GB HBM2e 8 GB GDDR6 16x more on MI250
Bandwidth 3,200 GB/s 272 GB/s 12x higher on MI250
Bus width 8,192-bit 128-bit 64x wider on MI250
Compute · dense
FP8 Not supported 60.5 TFLOPS RTX 4060 only
FP16 / BF16 362.1 TFLOPS 30.2 TFLOPS 12x higher on MI250
INT8 362.1 TOPS 120.9 TOPS 3x higher on MI250
FP32 90.5 TFLOPS 15.1 TFLOPS 6x higher on MI250
FP64 45.3 TFLOPS Not supported MI250 only
Platform
Interconnect Infinity Fabric 400 GB/s PCIe only Infinity Fabric on MI250 only
Board power 500 W 115 W 4.3x higher on MI250
Released Q4 2021 Q2 2023 2 years newer on RTX 4060
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP8FP16BF16TF32FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and RTX 4060 datasheet.

Where to rent them

Providers listing these GPUs, those with both first, so you can switch without moving clouds.

Provider MI250 /GPU/hr RTX 4060 /GPU/hr
Cirrascale logo Cirrascale Reserved (12mo) $1.30 --
Salad logo Salad -- On-Demand $0.08
Theta EdgeCloud logo Theta EdgeCloud -- On-Demand $0.12
Database Mart logo Database Mart -- Reserved (24mo) $0.21

Similar GPUs

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Our data for AMD MI250 was last updated on Sept. 7, 2026, and for Nvidia RTX 4060 on Sept. 7, 2026.