AMD logo AMD MI250 vs Nvidia logo Nvidia GB300

The GB300 is newer, with 2.2x the memory and 2.5x the bandwidth.

At a glance

Memory

2.2x more on GB300

MI250
128 GB
GB300
288 GB

Memory bandwidth

2.5x higher on GB300

MI250
3.20 TB/s
GB300
8.00 TB/s

Cheapest on-demand

MI250 is not sold on demand

MI250
--
GB300
$18.00 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI250 GB300 Difference
On-demand No on-demand listings -- /GPU/hr from $18.00
Reserved -- /GPU/hr from $1.30 (12 mo) On request
Spot No spot listings Sold out

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved on the MI250 and on-demand on the GB300: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI250 vs GB300 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 GB300 Difference
Memory
Capacity 128 GB HBM2e 288 GB HBM3e 2.2x more on GB300
Bandwidth 3,200 GB/s 8,000 GB/s 2.5x higher on GB300
Bus width 8,192-bit 8,192-bit Identical
Compute · dense
FP4 Not supported 15,000 TFLOPS GB300 only
FP8 Not supported 5,000 TFLOPS GB300 only
FP16 / BF16 362.1 TFLOPS 2,500 TFLOPS 6.9x higher on GB300
INT8 362.1 TOPS 165 TOPS 2.2x higher on MI250
FP32 90.5 TFLOPS 80 TFLOPS 13% higher on MI250
FP64 45.3 TFLOPS 1.3 TFLOPS 35x higher on MI250
Platform
Interconnect Infinity Fabric 400 GB/s NVLink 1,800 GB/s 4.5x higher on GB300
Board power 500 W 1,400 W 2.8x higher on GB300
Released Q4 2021 Q1 2025 3 years newer on GB300
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP4FP6FP8FP16BF16TF32FP32FP64INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and GB300 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI250 was last updated on Sept. 14, 2026, and for Nvidia GB300 on Sept. 14, 2026.