The MI355X is newer, with 2.2x the memory and 2.5x the bandwidth.

At a glance

Memory

2.2x more on MI355X

MI250
128 GB
MI355X
288 GB

Memory bandwidth

2.5x higher on MI355X

MI250
3.20 TB/s
MI355X
8.00 TB/s

Cheapest on-demand

MI250 is not sold on demand

MI250
--
MI355X
$5.99 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI250 MI355X Difference
On-demand No on-demand listings -- /GPU/hr from $5.99
Reserved -- /GPU/hr from $1.30 (12 mo) No reserved listings
Spot No spot listings -- /GPU/hr from $2.97

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved on the MI250 and on-demand and spot on the MI355X: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI250 vs MI355X price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 MI355X Difference
Memory
Capacity 128 GB HBM2e 288 GB HBM3e 2.2x more on MI355X
Bandwidth 3,200 GB/s 8,000 GB/s 2.5x higher on MI355X
Bus width 8,192-bit 8,192-bit Identical
Compute · dense
FP4 Not supported 10,066.3 TFLOPS MI355X only
FP8 Not supported 5,033.2 TFLOPS MI355X only
FP16 / BF16 362.1 TFLOPS 2,516.6 TFLOPS 7x higher on MI355X
INT8 362.1 TOPS 5,033.2 TOPS 14x higher on MI355X
FP32 90.5 TFLOPS 157.3 TFLOPS 74% higher on MI355X
FP64 45.3 TFLOPS 78.6 TFLOPS 74% higher on MI355X
Platform
Interconnect Infinity Fabric 400 GB/s Infinity Fabric 1,075 GB/s 2.7x higher on MI355X
Board power 500 W 1,400 W 2.8x higher on MI355X
Released Q4 2021 Q2 2025 4 years newer on MI355X
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP4FP6FP8FP16BF16FP32FP64INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and MI355X datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI250 was last updated on Sept. 14, 2026, and for AMD MI355X on Sept. 14, 2026.