The MI350X is newer, with 2.2x the memory and 2.5x the bandwidth.

At a glance

Memory

2.2x more on MI350X

MI250
128 GB
MI350X
288 GB

Memory bandwidth

2.5x higher on MI350X

MI250
3.20 TB/s
MI350X
8.00 TB/s

Cheapest on-demand

MI250 and MI350X are not sold on demand

MI250
--
MI350X
--

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI250 MI350X Difference
Reserved -- /GPU/hr from $1.30 (12 mo) -- /GPU/hr from $4.76 (12 mo)
Spot No spot listings -- /GPU/hr from $2.46

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved on the MI250 and reserved and spot on the MI350X: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI250 vs MI350X price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 MI350X Difference
Memory
Capacity 128 GB HBM2e 288 GB HBM3e 2.2x more on MI350X
Bandwidth 3,200 GB/s 8,000 GB/s 2.5x higher on MI350X
Bus width 8,192-bit 8,192-bit Identical
Compute · dense
FP4 Not supported 9,227.5 TFLOPS MI350X only
FP8 Not supported 4,614 TFLOPS MI350X only
FP16 / BF16 362.1 TFLOPS 2,309.6 TFLOPS 6.4x higher on MI350X
INT8 362.1 TOPS 4,614 TOPS 13x higher on MI350X
FP32 90.5 TFLOPS 144.2 TFLOPS 59% higher on MI350X
FP64 45.3 TFLOPS 72.1 TFLOPS 59% higher on MI350X
Platform
Interconnect Infinity Fabric 400 GB/s Infinity Fabric 1,075 GB/s 2.7x higher on MI350X
Board power 500 W 1,000 W 2x higher on MI350X
Released Q4 2021 Q2 2025 4 years newer on MI350X
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP4FP6FP8FP16BF16FP32FP64INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and MI350X datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI250 was last updated on Sept. 14, 2026, and for AMD MI350X on Sept. 14, 2026.