The MI350P is newer, with 13% more memory and 25% more bandwidth.

At a glance

Memory

13% more on MI350P

MI250
128 GB
MI350P
144 GB

Memory bandwidth

25% higher on MI350P

MI250
3.20 TB/s
MI350P
4.00 TB/s

Cheapest on-demand

MI250
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MI350P
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Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Price history

MI250 vs MI350P price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI250 MI350P Difference
Memory
Capacity 128 GB HBM2e 144 GB HBM3e 13% more on MI350P
Bandwidth 3,200 GB/s 4,000 GB/s 25% higher on MI350P
Bus width 8,192-bit 4,096-bit 2x wider on MI250
Compute · dense
FP4 Not supported 4,600 TFLOPS MI350P only
FP8 Not supported 2,300 TFLOPS MI350P only
FP16 / BF16 362.1 TFLOPS 1,150 TFLOPS 3.2x higher on MI350P
INT8 362.1 TOPS 2,300 TOPS 6.4x higher on MI350P
FP32 90.5 TFLOPS 72 TFLOPS 26% higher on MI250
FP64 45.3 TFLOPS 36 TFLOPS 26% higher on MI250
Platform
Interconnect Infinity Fabric 400 GB/s PCIe only Infinity Fabric on MI250 only
Board power 500 W 600 W 20% higher on MI350P
Released Q4 2021 Q2 2026 4 years newer on MI350P
Precision
Supported formats FP16BF16FP32FP64INT4INT8 FP4FP6FP8FP16BF16FP32FP64INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI250 datasheet and MI350P datasheet.

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Our data for AMD MI250 was last updated on Sept. 14, 2026, and for AMD MI350P on Nov. 13, 2026.