AMD MI300X
vs
Nvidia RTX PRO 4500
A data center GPU against a workstation card, one CDNA 3 and one Blackwell: 192 GB HBM3 against 32 GB GDDR7, 5.9x the memory bandwidth on the MI300X, and Infinity Fabric 896 GB/s on the MI300X where the RTX PRO 4500 is PCIe only.
At a glance
Updated 5 minutes ago- Memory
- 192 GB
- HBM3
- Memory bandwidth
- 5.30 TB/s
- From
- $2.59 /GPU/hr
- 10 providers
- Memory
- 32 GB
- GDDR7
- Memory bandwidth
- 896 GB/s
- From
- $0.72 /GPU/hr
- 5 providers
Price comparison
Cheapest listed price per GPU per hour by billing type, and the median across providers.
| Billing | MI300X | RTX PRO 4500 | Difference |
|---|---|---|---|
| On-demand | $2.59 | $0.72 | 3.6x more expensive on MI300X |
| Spot | $1.60 | No spot listings | |
| Reserved | $1.61 | No reserved listings | |
| Median | $2.99 | $0.92 | 3.2x more expensive on MI300X |
Median: Median across providers, one vote each, so a large catalog does not outweigh a small one.
Price history
MI300X vs RTX PRO 4500 price history
Weekly median on-demand price per GPU per hour
Specs comparison
| Spec | MI300X | RTX PRO 4500 | Difference |
|---|---|---|---|
| Memory | |||
| Capacity | 192 GB HBM3 | 32 GB GDDR7 | 6x more on MI300X |
| Bandwidth | 5,300 GB/s | 896 GB/s | 5.9x higher on MI300X |
| Bus width | 8,192-bit | 256-bit | 32x wider on MI300X |
| Compute · dense | |||
| FP4 | Not supported | 808.5 TFLOPS | RTX PRO 4500 only |
| FP8 | 2,614.9 TFLOPS | 404.3 TFLOPS | 6.5x higher on MI300X |
| FP16 / BF16 | 1,307.4 TFLOPS | 202.1 TFLOPS | 6.5x higher on MI300X |
| INT8 | 2,614.9 TOPS | 404.3 TOPS | 6.5x higher on MI300X |
| FP32 | 163.4 TFLOPS | 51 TFLOPS | 3.2x higher on MI300X |
| FP64 | 81.7 TFLOPS | Not supported | MI300X only |
| Platform | |||
| Interconnect | Infinity Fabric 896 GB/s | PCIe only | Infinity Fabric on MI300X only |
| Board power | 750 W | 200 W | 3.8x higher on MI300X |
| Released | Q4 2023 | Q1 2025 | 15 months newer on RTX PRO 4500 |
| Precision | |||
| Supported formats | FP8FP16BF16TF32FP32FP64INT8 | FP4FP8FP16BF16TF32FP32INT8 | |
Compute: Vendor peak figures, dense and per GPU. Not measured throughput.
Source: MI300X datasheet and RTX PRO 4500 datasheet.
Where to rent them
Providers listing these GPUs, those with both first, so you can switch without moving clouds.
| Provider | MI300X /GPU/hr | RTX PRO 4500 /GPU/hr |
|---|---|---|
Runpod
|
Reservation on request | On-Demand $0.72 |
DigitalOcean
|
On-Demand $2.59 | -- |
Cyfuture AI
|
On-Demand $2.78 | -- |
Hot Aisle
|
On-Demand $2.99 | -- |
Oracle Cloud
|
On-Demand $6.00 | -- |
Azure
|
On-Demand $7.86 | -- |
Cirrascale
|
Reserved (12mo) $3.12 | -- |
Crusoe
|
Reservation on request | -- |
GPU.ai
|
-- | On-Demand $0.72 |
Massed Compute
|
-- | On-Demand $0.92 |
EmpirioLabs AI
|
-- | On-Demand $1.40 |
AWS
|
-- | On-Demand $2.52 |
10 providers list the MI300X and 5 the RTX PRO 4500. Every listing is on the MI300X page and the RTX PRO 4500 page.
Similar GPUs
Other comparisons in the same class.
Our data for AMD MI300X was last updated on Sept. 7, 2026, and for Nvidia RTX PRO 4500 on Sept. 7, 2026.