AMD logo AMD MI300X vs Nvidia logo Nvidia RTX 5080

The MI300X has 12x the memory and 5.5x the bandwidth. The RTX 5080 is newer and typically cheaper.

At a glance

Memory

12x more on MI300X

MI300X
192 GB
RTX 5080
16 GB

Memory bandwidth

5.5x higher on MI300X

MI300X
5,300 GB/s
RTX 5080
960 GB/s

Cheapest on-demand

92% cheaper on RTX 5080

MI300X
$2.59 /GPU/hr
RTX 5080
$0.20 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI300X RTX 5080 Difference
On-demand $4.41 /GPU/hr from $2.59 $0.30 /GPU/hr from $0.20 93% cheaper on RTX 5080
Reserved $3.39 /GPU/hr from $1.61 (12 mo) -- /GPU/hr from $0.27 (1 mo)
Spot -- /GPU/hr from $1.60 -- /GPU/hr from $0.15

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for spot on the MI300X and reserved and spot on the RTX 5080: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI300X vs RTX 5080 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI300X RTX 5080 Difference
Memory
Capacity 192 GB HBM3 16 GB GDDR7 12x more on MI300X
Bandwidth 5,300 GB/s 960 GB/s 5.5x higher on MI300X
Bus width 8,192-bit 256-bit 32x wider on MI300X
Compute · dense
FP4 Not supported 900.4 TFLOPS RTX 5080 only
FP8 2,614.9 TFLOPS 225.1 TFLOPS 12x higher on MI300X
FP16 / BF16 1,307.4 TFLOPS 112.6 TFLOPS 12x higher on MI300X
INT8 2,614.9 TOPS 450.2 TOPS 5.8x higher on MI300X
FP32 163.4 TFLOPS 56.3 TFLOPS 2.9x higher on MI300X
FP64 81.7 TFLOPS Not supported MI300X only
Platform
Interconnect Infinity Fabric 896 GB/s PCIe only Infinity Fabric on MI300X only
Board power 750 W 360 W 2.1x higher on MI300X
Released Q4 2023 Q1 2025 14 months newer on RTX 5080
Precision
Supported formats FP8FP16BF16TF32FP32FP64INT8 FP4FP8FP16BF16TF32FP32INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI300X datasheet and RTX 5080 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

11 providers list the MI300X and 6 the RTX 5080. Every listing is on the MI300X page and the RTX 5080 page.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI300X was last updated on Sept. 14, 2026, and for Nvidia RTX 5080 on Sept. 14, 2026.