Overview

AMD logo AMD MI250

Previous-gen AMD data center GPU for HPC and scientific computing.

High Performance Datacenter

Nvidia logo Nvidia RTX PRO 6000

Largest VRAM desktop workstation GPU for local AI and visualization.

Mid-Range Workstation

Memory per GPU

1.3x more on MI250
AMD logo MI250
128 GB HBM2e
Nvidia logo RTX PRO 6000
96 GB GDDR7

Memory bandwidth

1.8x higher on MI250
AMD logo MI250
3,200 GB/s
Nvidia logo RTX PRO 6000
1,792 GB/s

GPU interconnect

AMD logo MI250
Infinity Fabric 400 GB/s
Nvidia logo RTX PRO 6000
PCIe only

Precision support

AMD logo MI250
FP16 BF16 FP32 FP64 INT4 INT8
Nvidia logo RTX PRO 6000
FP4 FP8 FP16 BF16 TF32 FP32 INT8

Highlighted formats are supported by only one of the two.

Architecture

AMD logo MI250
CDNA2
Nvidia logo RTX PRO 6000
Blackwell

Released

3 years newer on RTX PRO 6000
AMD logo MI250
Q4 2021
Nvidia logo RTX PRO 6000
Q1 2025

Price comparison

Cheapest on-demand

AMD logo MI250
Not sold on demand
Nvidia logo RTX PRO 6000
$0.66 / GPU / hr

Typical rate

1.5x higher on RTX PRO 6000
AMD logo MI250
$1.50 / GPU / hr
Nvidia logo RTX PRO 6000
$2.19 / GPU / hr

Median across providers, one vote each, so a large catalog does not outweigh a small one.

Spot floor

AMD logo MI250
No spot listings
Nvidia logo RTX PRO 6000
$0.17 / GPU / hr

Full price range

AMD logo MI250
$1.30 - $1.62 / GPU / hr
Nvidia logo RTX PRO 6000
$0.17 - $17.27 / GPU / hr

Lowest to highest listing per GPU-hour, across on-demand, spot, reserved and custom.

Providers listing it

33 more on RTX PRO 6000
AMD logo MI250
1
Nvidia logo RTX PRO 6000
34

Price, last 90 days

AMD logo MI250
Not tracked yet
Nvidia logo RTX PRO 6000
+11%

Change in the market-wide median, which moves when providers reprice and when cheaper or more expensive listings enter the market. Withheld where too few providers price the card, its history is too short, or its weekly print swings too hard to read as a trend.

Heads up: We do our best to keep these specs & prices accurate. However, cloud costs may fluctuate based on region, usage, and other factors not listed here. These are estimates based on common setups and are for informational purposes only. Always verify current rates & exact specs with the provider before provisioning.

Offers and availability

How this list works

Order

Each provider appears once per GPU. We pick the one configuration that speaks for that provider, and rank on it in this order:

  1. Availability: in stock, then waitlist, then not reported, then out of stock. A price you can act on outranks a cheaper one you cannot.
  2. Billing type: on-demand first, then reserved, then spot, then quote-only. On-demand leads because it is the only rate you can hold without committing to anything.
  3. Price: the lowest per-GPU hourly rate the provider lists, converted to USD.

The configuration we pick is chosen the same way, availability before billing before price. The rest of that provider's configurations are on the GPU's own page.

Ties sort alphabetically. Reserved rates are not separated by term length, so a three-year commitment can sit above a one-month one: the label beneath each price says which you are looking at. Providers who publish no rate are listed last within their group.

Transparency and funding

  • Ads and sponsors: Paid placements sit at the top of the list and are always labeled as sponsored content. Sponsorship never influences the organic ranking itself.
  • Affiliates: Affiliate links are marked. We may earn a commission if you click them, but commissions never affect the order.
  • Prices: Shown in USD, converted at daily reference rates where a provider publishes in another currency. A month means 720 hours. How we estimate costs.

Similar GPUs

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Our data for AMD MI250 was last updated on Aug. 21, 2026, and for Nvidia RTX PRO 6000 on Aug. 21, 2026.