AMD MI355X
vs
Nvidia RTX PRO 4000
A data center GPU against a workstation card, one CDNA 4 and one Blackwell: 288 GB HBM3e against 24 GB GDDR7, 12x the memory bandwidth on the MI355X, and Infinity Fabric 1,075 GB/s on the MI355X where the RTX PRO 4000 is PCIe only.
At a glance
Memory
- MI355X
- 288 GB
- RTX PRO 4000
- 24 GB
12x more on MI355X
Memory bandwidth
- MI355X
- 8,000 GB/s
- RTX PRO 4000
- 672 GB/s
12x higher on MI355X
Cheapest on-demand
- MI355X
- $8.60 /GPU/hr
- RTX PRO 4000
- $10.13 /GPU/hr
15% cheaper on MI355X
Price comparison
Median price per GPU per hour by billing type, with the cheapest listing under it.
| Billing | MI355X | RTX PRO 4000 | Difference |
|---|---|---|---|
| On-demand | -- /GPU/hr from $8.60 | -- /GPU/hr from $10.13 | |
| Reserved | No reserved listings | -- /GPU/hr from $0.26 (24 mo) | |
| Spot | -- /GPU/hr from $4.50 | -- /GPU/hr from $0.19 |
Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for on-demand and spot on the MI355X and on-demand, reserved and spot on the RTX PRO 4000: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.
Price history
MI355X vs RTX PRO 4000 price history
Weekly median on-demand price per GPU per hour
Specs comparison
| Spec | MI355X | RTX PRO 4000 | Difference |
|---|---|---|---|
| Memory | |||
| Capacity | 288 GB HBM3e | 24 GB GDDR7 | 12x more on MI355X |
| Bandwidth | 8,000 GB/s | 672 GB/s | 12x higher on MI355X |
| Bus width | 8,192-bit | 192-bit | 43x wider on MI355X |
| Compute · dense | |||
| FP4 | 10,066.3 TFLOPS | 589 TFLOPS | 17x higher on MI355X |
| FP8 | 5,033.2 TFLOPS | 294.5 TFLOPS | 17x higher on MI355X |
| FP16 / BF16 | 2,516.6 TFLOPS | 147.3 TFLOPS | 17x higher on MI355X |
| INT8 | 5,033.2 TOPS | 294.5 TOPS | 17x higher on MI355X |
| FP32 | 157.3 TFLOPS | 37 TFLOPS | 4.3x higher on MI355X |
| FP64 | 78.6 TFLOPS | Not supported | MI355X only |
| Platform | |||
| Interconnect | Infinity Fabric 1,075 GB/s | PCIe only | Infinity Fabric on MI355X only |
| Board power | 1,400 W | 145 W | 9.7x higher on MI355X |
| Released | Q2 2025 | Q1 2025 | |
| Precision | |||
| Supported formats | FP4FP6FP8FP16BF16FP32FP64INT8 | FP4FP8FP16BF16TF32FP32INT8 | |
Compute: Vendor peak figures, dense and per GPU. Not measured throughput.
Source: MI355X datasheet and RTX PRO 4000 datasheet.
Where to rent them
Providers listing these GPUs, those with both first, so you can switch without moving clouds.
| Provider | MI355X /GPU/hr | RTX PRO 4000 /GPU/hr |
|---|---|---|
Oracle Cloud
|
On-Demand $8.60 | -- |
DigitalOcean
|
Spot $4.50 | -- |
TensorWave
|
Custom $2.95 | -- |
Vultr
|
Spot $2.59 | -- |
Vast.ai
|
-- | On-Demand $10.13 |
Database Mart
|
-- | Reserved (24mo) $0.26 |
Runpod
|
-- | Reservation on request |
Similar GPUs
Other comparisons in the same class.
Our data for AMD MI355X was last updated on Sept. 7, 2026, and for Nvidia RTX PRO 4000 on Sept. 7, 2026.