AMD logo AMD MI355X vs Nvidia logo Nvidia Quadro RTX 6000

The MI355X is newer, with 12x the memory and 12x the bandwidth. The Quadro RTX 6000 is cheaper right now.

At a glance

Memory

12x more on MI355X

MI355X
288 GB
Quadro RTX 6000
24 GB

Memory bandwidth

12x higher on MI355X

MI355X
8,000 GB/s
Quadro RTX 6000
672 GB/s

Cheapest on-demand

98% cheaper on Quadro RTX 6000

MI355X
$5.99 /GPU/hr
Quadro RTX 6000
$0.13 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI355X Quadro RTX 6000 Difference
On-demand -- /GPU/hr from $5.99 -- /GPU/hr from $0.13
Reserved No reserved listings -- /GPU/hr from $0.12 (12 mo)
Spot -- /GPU/hr from $2.97 -- /GPU/hr from $0.11

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for on-demand and spot on the MI355X and on-demand, reserved and spot on the Quadro RTX 6000: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI355X vs Quadro RTX 6000 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI355X Quadro RTX 6000 Difference
Memory
Capacity 288 GB HBM3e 24 GB GDDR6 12x more on MI355X
Bandwidth 8,000 GB/s 672 GB/s 12x higher on MI355X
Bus width 8,192-bit 384-bit 21x wider on MI355X
Compute · dense
FP4 10,066.3 TFLOPS Not supported MI355X only
FP8 5,033.2 TFLOPS Not supported MI355X only
FP16 / BF16 2,516.6 TFLOPS 130.5 TFLOPS 19x higher on MI355X
INT8 5,033.2 TOPS 261 TOPS 19x higher on MI355X
FP32 157.3 TFLOPS 16.3 TFLOPS 9.7x higher on MI355X
FP64 78.6 TFLOPS Not supported MI355X only
Platform
Interconnect Infinity Fabric 1,075 GB/s NVLink 100 GB/s 11x higher on MI355X
Board power 1,400 W 295 W 4.7x higher on MI355X
Released Q2 2025 Q3 2018 7 years newer on MI355X
Precision
Supported formats FP4FP6FP8FP16BF16FP32FP64INT8 FP16FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI355X datasheet and Quadro RTX 6000 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI355X was last updated on Sept. 14, 2026, and for Nvidia Quadro RTX 6000 on Sept. 14, 2026.