AMD logo AMD MI355X vs Nvidia logo Nvidia RTX 4080

The MI355X is newer, with 18x the memory and 11x the bandwidth. The RTX 4080 is cheaper right now.

At a glance

Memory

18x more on MI355X

MI355X
288 GB
RTX 4080
16 GB

Memory bandwidth

11x higher on MI355X

MI355X
8,000 GB/s
RTX 4080
717 GB/s

Cheapest on-demand

97% cheaper on RTX 4080

MI355X
$5.99 /GPU/hr
RTX 4080
$0.19 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI355X RTX 4080 Difference
On-demand -- /GPU/hr from $5.99 $0.26 /GPU/hr from $0.19
Reserved No reserved listings -- /GPU/hr from $0.21 (1 mo)
Spot -- /GPU/hr from $2.97 -- /GPU/hr from $0.11

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for on-demand and spot on the MI355X and reserved and spot on the RTX 4080: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI355X vs RTX 4080 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI355X RTX 4080 Difference
Memory
Capacity 288 GB HBM3e 16 GB GDDR6X 18x more on MI355X
Bandwidth 8,000 GB/s 717 GB/s 11x higher on MI355X
Bus width 8,192-bit 256-bit 32x wider on MI355X
Compute · dense
FP4 10,066.3 TFLOPS Not supported MI355X only
FP8 5,033.2 TFLOPS 194.9 TFLOPS 26x higher on MI355X
FP16 / BF16 2,516.6 TFLOPS 97.5 TFLOPS 26x higher on MI355X
INT8 5,033.2 TOPS 389.9 TOPS 13x higher on MI355X
FP32 157.3 TFLOPS 48.7 TFLOPS 3.2x higher on MI355X
FP64 78.6 TFLOPS Not supported MI355X only
Platform
Interconnect Infinity Fabric 1,075 GB/s PCIe only Infinity Fabric on MI355X only
Board power 1,400 W 320 W 4.4x higher on MI355X
Released Q2 2025 Q4 2022 3 years newer on MI355X
Precision
Supported formats FP4FP6FP8FP16BF16FP32FP64INT8 FP8FP16BF16TF32FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI355X datasheet and RTX 4080 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI355X was last updated on Sept. 14, 2026, and for Nvidia RTX 4080 on Sept. 14, 2026.