AMD logo AMD MI350X vs Nvidia logo Nvidia RTX 4500 Ada

The MI350X is newer, with 12x the memory and 19x the bandwidth.

At a glance

Memory

12x more on MI350X

MI350X
288 GB
RTX 4500 Ada
24 GB

Memory bandwidth

19x higher on MI350X

MI350X
8,000 GB/s
RTX 4500 Ada
432 GB/s

Cheapest on-demand

MI350X is not sold on demand

MI350X
--
RTX 4500 Ada
$0.33 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI350X RTX 4500 Ada Difference
On-demand No on-demand listings -- /GPU/hr from $0.33
Reserved -- /GPU/hr from $4.76 (12 mo) -- /GPU/hr from $0.30 (1 mo)
Spot -- /GPU/hr from $2.46 -- /GPU/hr from $0.13

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved and spot on the MI350X and on-demand, reserved and spot on the RTX 4500 Ada: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI350X vs RTX 4500 Ada price history

Weekly median on-demand price per GPU per hour

Last 9 months
Aggregating historical prices...

Specs comparison

Spec MI350X RTX 4500 Ada Difference
Memory
Capacity 288 GB HBM3e 24 GB GDDR6 12x more on MI350X
Bandwidth 8,000 GB/s 432 GB/s 19x higher on MI350X
Bus width 8,192-bit 192-bit 43x wider on MI350X
Compute · dense
FP4 9,227.5 TFLOPS Not supported MI350X only
FP8 4,614 TFLOPS 317 TFLOPS 15x higher on MI350X
FP16 / BF16 2,309.6 TFLOPS 158.5 TFLOPS 15x higher on MI350X
INT8 4,614 TOPS
FP32 144.2 TFLOPS 39.6 TFLOPS 3.6x higher on MI350X
FP64 72.1 TFLOPS Not supported MI350X only
Platform
Interconnect Infinity Fabric 1,075 GB/s PCIe only Infinity Fabric on MI350X only
Board power 1,000 W 210 W 4.8x higher on MI350X
Released Q2 2025 Q3 2023 2 years newer on MI350X
Precision
Supported formats FP4FP6FP8FP16BF16FP32FP64INT8 FP8FP16BF16TF32FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI350X datasheet and RTX 4500 Ada datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI350X was last updated on Sept. 14, 2026, and for Nvidia RTX 4500 Ada on Sept. 14, 2026.