AMD logo AMD MI350X vs Nvidia logo Nvidia B300

Two data center GPUs, one CDNA 4 and one Blackwell Ultra: both with 288 GB HBM3e and 8,000 GB/s memory bandwidth, released 3 months apart.

At a glance

Memory

MI350X
288 GB
B300
288 GB

Identical

Memory bandwidth

MI350X
8.00 TB/s
B300
8.00 TB/s

Identical

Cheapest on-demand

MI350X
--
B300
$6.50 /GPU/hr

MI350X is not sold on demand

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI350X B300 Difference
On-demand No on-demand listings $7.89 /GPU/hr from $6.50
Reserved -- /GPU/hr from $4.76 (12 mo) $5.70 /GPU/hr from $4.25
Spot -- /GPU/hr from $4.00 $5.71 /GPU/hr from $4.30

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved and spot on the MI350X: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI350X vs B300 price history

Weekly median on-demand price per GPU per hour

Last 10 months
Aggregating historical prices...

Specs comparison

Spec MI350X B300 Difference
Memory
Capacity 288 GB HBM3e 288 GB HBM3e Identical
Bandwidth 8,000 GB/s 8,000 GB/s Identical
Bus width 8,192-bit 8,192-bit Identical
Compute · dense
FP4 9,227.5 TFLOPS 14,000 TFLOPS 1.5x higher on B300
FP8 4,614 TFLOPS 4,500 TFLOPS Within 5%
FP16 / BF16 2,309.6 TFLOPS 2,250 TFLOPS Within 5%
INT8 4,614 TOPS 153.5 TOPS 30x higher on MI350X
FP32 144.2 TFLOPS 75 TFLOPS 1.9x higher on MI350X
FP64 72.1 TFLOPS 1.2 TFLOPS 60x higher on MI350X
Platform
Interconnect Infinity Fabric 1,075 GB/s NVLink 1,800 GB/s 1.7x higher on B300
Board power 1,000 W 1,100 W 1.1x higher on B300
Released Q2 2025 Q1 2025
Precision
Supported formats FP4FP6FP8FP16BF16FP32FP64INT8 FP4FP6FP8FP16BF16TF32FP32FP64INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI350X datasheet and B300 datasheet.

Where to rent them

Providers listing these GPUs, those with both first, so you can switch without moving clouds.

Provider MI350X /GPU/hr B300 /GPU/hr
DigitalOcean logo DigitalOcean Reserved (12mo) $4.76 --
GPU.ai logo GPU.ai -- On-Demand $7.89
Runpod logo Runpod -- On-Demand $7.89
Lium logo Lium -- On-Demand $8.00
Vast.ai logo Vast.ai -- On-Demand $9.38
EmpirioLabs AI logo EmpirioLabs AI -- On-Demand $16.00
TheAI Cloud logo TheAI Cloud -- Reserved (24mo) $4.90
GPUaaS logo GPUaaS -- Custom on request
Packet·ai logo Packet·ai -- Custom on request

1 provider list the MI350X and 31 the B300. Every listing is on the MI350X page and the B300 page.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI350X was last updated on Sept. 14, 2026, and for Nvidia B300 on Sept. 14, 2026.