AMD MI350X
vs
Nvidia A4500
A data center GPU against a workstation card, one CDNA 4 and one Ampere: 288 GB HBM3e against 20 GB GDDR6, 12x the memory bandwidth on the MI350X, and Infinity Fabric 1,075 GB/s on the MI350X where the A4500 is PCIe only.
At a glance
Memory
- MI350X
- 288 GB
- A4500
- 20 GB
14x more on MI350X
Memory bandwidth
- MI350X
- 8,000 GB/s
- A4500
- 640 GB/s
12x higher on MI350X
Cheapest on-demand
- MI350X
- --
- A4500
- $0.25 /GPU/hr
MI350X is not sold on demand
Price comparison
Median price per GPU per hour by billing type, with the cheapest listing under it.
| Billing | MI350X | A4500 | Difference |
|---|---|---|---|
| On-demand | No on-demand listings | -- /GPU/hr from $0.25 | |
| Reserved | -- /GPU/hr from $4.76 (12 mo) | On request | |
| Spot | -- /GPU/hr from $4.00 | No spot listings |
Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved and spot on the MI350X and on-demand on the A4500: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.
Price history
MI350X vs A4500 price history
Weekly median on-demand price per GPU per hour
Specs comparison
| Spec | MI350X | A4500 | Difference |
|---|---|---|---|
| Memory | |||
| Capacity | 288 GB HBM3e | 20 GB GDDR6 | 14x more on MI350X |
| Bandwidth | 8,000 GB/s | 640 GB/s | 12x higher on MI350X |
| Bus width | 8,192-bit | 320-bit | 26x wider on MI350X |
| Compute · dense | |||
| FP4 | 9,227.5 TFLOPS | Not supported | MI350X only |
| FP8 | 4,614 TFLOPS | Not supported | MI350X only |
| FP16 / BF16 | 2,309.6 TFLOPS | 94.6 TFLOPS | 24x higher on MI350X |
| INT8 | 4,614 TOPS | ||
| FP32 | 144.2 TFLOPS | 23.7 TFLOPS | 6.1x higher on MI350X |
| FP64 | 72.1 TFLOPS | Not supported | MI350X only |
| Platform | |||
| Interconnect | Infinity Fabric 1,075 GB/s | PCIe only | Infinity Fabric on MI350X only |
| Board power | 1,000 W | 200 W | 5x higher on MI350X |
| Released | Q2 2025 | Q4 2021 | 4 years newer on MI350X |
| Precision | |||
| Supported formats | FP4FP6FP8FP16BF16FP32FP64INT8 | FP16BF16TF32FP32INT4INT8 | |
Compute: Vendor peak figures, dense and per GPU. Not measured throughput.
Source: MI350X datasheet and A4500 datasheet.
Where to rent them
Providers listing these GPUs, those with both first, so you can switch without moving clouds.
| Provider | MI350X /GPU/hr | A4500 /GPU/hr |
|---|---|---|
DigitalOcean
|
Reserved (12mo) $4.76 | -- |
GPU.ai
|
-- | On-Demand $0.25 |
Runpod
|
-- | Reservation on request |
Similar GPUs
Other comparisons in the same class.
-
Nvidia B200
180 GB HBM3e · released Q1 2024
From $3.75 /GPU/hr Compare
-
Nvidia H200
141 GB HBM3e · 40% less bandwidth than the MI350X
From $2.09 /GPU/hr Compare
-
AMD MI355X
288 GB HBM3e · released Q2 2025
From $8.60 /GPU/hr Compare
-
Nvidia L4
24 GB GDDR6 · 53% less bandwidth than the A4500
From $0.27 /GPU/hr Compare
-
Nvidia A10
24 GB GDDR6 · data center card
From $0.24 /GPU/hr Compare
Our data for AMD MI350X was last updated on Sept. 14, 2026, and for Nvidia A4500 on Sept. 14, 2026.