AMD MI350P vs Nvidia RTX PRO 4000 SFF

The MI350P has 6x the memory and 9.3x the bandwidth.

At a glance

Memory

6x more on MI350P

MI350P: 144 GB

RTX PRO 4000 SFF: 24 GB

Memory bandwidth

9.3x higher on MI350P

MI350P: 4,000 GB/s

RTX PRO 4000 SFF: 432 GB/s

Cheapest on-demand

MI350P: --

RTX PRO 4000 SFF: $0.38 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing	MI350P	RTX PRO 4000 SFF	Difference
On-demand	No on-demand listings	-- /GPU/hr from $0.38

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for on-demand on the RTX PRO 4000 SFF: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Specs comparison

Spec	MI350P	RTX PRO 4000 SFF	Difference
Memory
Capacity	144 GB HBM3e	24 GB GDDR7	6x more on MI350P
Bandwidth	4,000 GB/s	432 GB/s	9.3x higher on MI350P
Bus width	4,096-bit	192-bit	21x wider on MI350P
Compute · dense
FP4	4,600 TFLOPS	385 TFLOPS	12x higher on MI350P
FP8	2,300 TFLOPS	192.5 TFLOPS	12x higher on MI350P
FP16 / BF16	1,150 TFLOPS	96.3 TFLOPS	12x higher on MI350P
INT8	2,300 TOPS	192.5 TOPS	12x higher on MI350P
FP32	72 TFLOPS	24 TFLOPS	3x higher on MI350P
FP64	36 TFLOPS	Not supported	MI350P only
Platform
Interconnect	PCIe only	PCIe only
Board power	600 W	70 W	8.6x higher on MI350P
Released	Q2 2026	Q3 2025	9 months newer on MI350P
Precision
Supported formats	FP4FP6FP8FP16BF16FP32FP64INT8	FP4FP8FP16BF16TF32FP32INT8