AMD MI350P vs Nvidia Quadro RTX 6000

The MI350P is newer, with 6x the memory and 6x the bandwidth.

At a glance

Memory

6x more on MI350P

MI350P: 144 GB

Quadro RTX 6000: 24 GB

Memory bandwidth

6x higher on MI350P

MI350P: 4,000 GB/s

Quadro RTX 6000: 672 GB/s

Cheapest on-demand

MI350P: --

Quadro RTX 6000: $0.32 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing	MI350P	Quadro RTX 6000	Difference
On-demand	No on-demand listings	-- /GPU/hr from $0.32
Reserved	No reserved listings	-- /GPU/hr from $0.28 (12 mo)

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for on-demand and reserved on the Quadro RTX 6000: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI350P vs Quadro RTX 6000 price history

Weekly median on-demand price per GPU per hour

Last 12 months

Aggregating historical prices...

Specs comparison

Spec	MI350P	Quadro RTX 6000	Difference
Memory
Capacity	144 GB HBM3e	24 GB GDDR6	6x more on MI350P
Bandwidth	4,000 GB/s	672 GB/s	6x higher on MI350P
Bus width	4,096-bit	384-bit	11x wider on MI350P
Compute · dense
FP4	4,600 TFLOPS	Not supported	MI350P only
FP8	2,300 TFLOPS	Not supported	MI350P only
FP16 / BF16	1,150 TFLOPS	130.5 TFLOPS	8.8x higher on MI350P
INT8	2,300 TOPS	261 TOPS	8.8x higher on MI350P
FP32	72 TFLOPS	16.3 TFLOPS	4.4x higher on MI350P
FP64	36 TFLOPS	Not supported	MI350P only
Platform
Interconnect	PCIe only	NVLink 100 GB/s	NVLink on Quadro RTX 6000 only
Board power	600 W	295 W	2x higher on MI350P
Released	Q2 2026	Q3 2018	8 years newer on MI350P
Precision
Supported formats	FP4FP6FP8FP16BF16FP32FP64INT8	FP16FP32INT4INT8