AMD logo AMD MI350P vs Nvidia logo Nvidia RTX 5080

The MI350P is newer, with 9x the memory and 4.2x the bandwidth.

At a glance

Memory

9x more on MI350P

MI350P
144 GB
RTX 5080
16 GB

Memory bandwidth

4.2x higher on MI350P

MI350P
4,000 GB/s
RTX 5080
960 GB/s

Cheapest on-demand

MI350P
--
RTX 5080
$0.23 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI350P RTX 5080 Difference
On-demand No on-demand listings $0.34 /GPU/hr from $0.23
Spot No spot listings -- /GPU/hr from $0.15

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for spot on the RTX 5080: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI350P vs RTX 5080 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI350P RTX 5080 Difference
Memory
Capacity 144 GB HBM3e 16 GB GDDR7 9x more on MI350P
Bandwidth 4,000 GB/s 960 GB/s 4.2x higher on MI350P
Bus width 4,096-bit 256-bit 16x wider on MI350P
Compute · dense
FP4 4,600 TFLOPS 900.4 TFLOPS 5.1x higher on MI350P
FP8 2,300 TFLOPS 225.1 TFLOPS 10x higher on MI350P
FP16 / BF16 1,150 TFLOPS 112.6 TFLOPS 10x higher on MI350P
INT8 2,300 TOPS 450.2 TOPS 5.1x higher on MI350P
FP32 72 TFLOPS 56.3 TFLOPS 28% higher on MI350P
FP64 36 TFLOPS Not supported MI350P only
Platform
Interconnect PCIe only PCIe only
Board power 600 W 360 W 67% higher on MI350P
Released Q2 2026 Q1 2025 15 months newer on MI350P
Precision
Supported formats FP4FP6FP8FP16BF16FP32FP64INT8 FP4FP8FP16BF16TF32FP32INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI350P datasheet and RTX 5080 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI350P was last updated on Nov. 13, 2026, and for Nvidia RTX 5080 on Sept. 14, 2026.