AMD MI350P vs Nvidia RTX 4080

The MI350P is newer, with 9x the memory and 5.6x the bandwidth.

At a glance

Memory

9x more on MI350P

MI350P: 144 GB

RTX 4080: 16 GB

Memory bandwidth

5.6x higher on MI350P

MI350P: 4,000 GB/s

RTX 4080: 717 GB/s

Cheapest on-demand

MI350P: --

RTX 4080: $0.25 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing	MI350P	RTX 4080	Difference
On-demand	No on-demand listings	$0.29 /GPU/hr from $0.25
Spot	No spot listings	-- /GPU/hr from $0.11

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for spot on the RTX 4080: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI350P vs RTX 4080 price history

Weekly median on-demand price per GPU per hour

Last 12 months

Aggregating historical prices...

Specs comparison

Spec	MI350P	RTX 4080	Difference
Memory
Capacity	144 GB HBM3e	16 GB GDDR6X	9x more on MI350P
Bandwidth	4,000 GB/s	717 GB/s	5.6x higher on MI350P
Bus width	4,096-bit	256-bit	16x wider on MI350P
Compute · dense
FP4	4,600 TFLOPS	Not supported	MI350P only
FP8	2,300 TFLOPS	194.9 TFLOPS	12x higher on MI350P
FP16 / BF16	1,150 TFLOPS	97.5 TFLOPS	12x higher on MI350P
INT8	2,300 TOPS	389.9 TOPS	5.9x higher on MI350P
FP32	72 TFLOPS	48.7 TFLOPS	48% higher on MI350P
FP64	36 TFLOPS	Not supported	MI350P only
Platform
Interconnect	PCIe only	PCIe only
Board power	600 W	320 W	88% higher on MI350P
Released	Q2 2026	Q4 2022	4 years newer on MI350P
Precision
Supported formats	FP4FP6FP8FP16BF16FP32FP64INT8	FP8FP16BF16TF32FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI350P datasheet and RTX 4080 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Provider	MI350P	RTX 4080
Theta EdgeCloud Distributed	--	$0.25 /GPU/hr On-demand
Salad Distributed	--	$0.27 /GPU/hr On-demand
Runpod USA	--	$0.28 /GPU/hr On-demand
GPUhub Singapore	--	$0.30 /GPU/hr On-demand
GPU.ai UAE	--	$0.31 /GPU/hr On-demand
SwissGPU Switzerland	--	$0.42 /GPU/hr On-demand