AMD logo AMD MI325X vs Nvidia logo Nvidia RTX 4080

The MI325X is newer, with 16x the memory and 8.4x the bandwidth. The RTX 4080 is typically cheaper.

At a glance

Memory

16x more on MI325X

MI325X
256 GB
RTX 4080
16 GB

Memory bandwidth

8.4x higher on MI325X

MI325X
6,000 GB/s
RTX 4080
717 GB/s

Cheapest on-demand

90% cheaper on RTX 4080

MI325X
$2.25 /GPU/hr
RTX 4080
$0.21 /GPU/hr

Price comparison

Median price per GPU per hour by billing type, with the cheapest listing under it.

Billing MI325X RTX 4080 Difference
On-demand $3.06 /GPU/hr from $2.25 $0.24 /GPU/hr from $0.21 92% cheaper on RTX 4080
Reserved $1.95 /GPU/hr from $1.48 (12 mo) -- /GPU/hr from $0.25 (3 mo)
Spot Sold out -- /GPU/hr from $0.11

Heads up: A provider's own page may quote a different figure, for example on tax, region or a promotion. A monthly-only plan shows a derived hourly rate. Medians are across providers, one vote each, so a large catalog does not outweigh a small one. No median for reserved and spot on the RTX 4080: we only show one when at least 3 providers list the GPU on that billing type. Verify before provisioning. More on how we price.

Price history

MI325X vs RTX 4080 price history

Weekly median on-demand price per GPU per hour

Last 12 months
Aggregating historical prices...

Specs comparison

Spec MI325X RTX 4080 Difference
Memory
Capacity 256 GB HBM3e 16 GB GDDR6X 16x more on MI325X
Bandwidth 6,000 GB/s 717 GB/s 8.4x higher on MI325X
Bus width 8,192-bit 256-bit 32x wider on MI325X
Compute · dense
FP8 2,614.9 TFLOPS 194.9 TFLOPS 13x higher on MI325X
FP16 / BF16 1,307.4 TFLOPS 97.5 TFLOPS 13x higher on MI325X
INT8 2,614.9 TOPS 389.9 TOPS 6.7x higher on MI325X
FP32 163.4 TFLOPS 48.7 TFLOPS 3.4x higher on MI325X
FP64 81.7 TFLOPS Not supported MI325X only
Platform
Interconnect Infinity Fabric 896 GB/s PCIe only Infinity Fabric on MI325X only
Board power 1,000 W 320 W 3.1x higher on MI325X
Released Q4 2024 Q4 2022 2 years newer on MI325X
Precision
Supported formats FP8FP16BF16TF32FP32FP64INT8 FP8FP16BF16TF32FP32INT4INT8

Compute: Vendor peak figures, dense and per GPU. Not measured throughput.

Source: MI325X datasheet and RTX 4080 datasheet.

Where to rent them

Providers that rent these GPUs, with each one's cheapest rate. No provider we track offers both right now.

Similar GPUs

Other comparisons in the same class.

Our data for AMD MI325X was last updated on Sept. 14, 2026, and for Nvidia RTX 4080 on Sept. 14, 2026.